d2_cluster: A Validated Method for Clustering EST and Full-Length cDNA Sequences
نویسندگان
چکیده
منابع مشابه
d2_cluster: a validated method for clustering EST and full-length cDNAsequences.
Several efforts are under way to condense single-read expressed sequence tags (ESTs) and full-length transcript data on a large scale by means of clustering or assembly. One goal of these projects is the construction of gene indices where transcripts are partitioned into index classes (or clusters) such that they are put into the same index class if and only if they represent the same gene. Acc...
متن کاملTargetIdentifier: a webserver for identifying full-length cDNAs from EST sequences
TargetIdentifier is a webserver that identifies full-length cDNA sequences from the expressed sequence tag (EST)-derived contig and singleton data. To accomplish this TargetIdentifier uses BLASTX alignments as a guide to locate protein coding regions and potential start and stop codons. This information is then used to determine whether the EST-derived sequences include their translation start ...
متن کاملTargetFinder and Annotator: a Simple Approach for Finding Full-length Target cDNAs and for Annotating EST Sequences
In a large scale EST (expressed sequence tag) or cDNA sequencing project, it is often desirable to know whether the ESTs identify genes of interest and whether the cloned cDNAs include intact coding regions (are of full-length). In this work, we present two Perl tools, TargetFinder and Annotator. TargetFinder automates the identification of full-length cDNAs from assembled EST sequences includi...
متن کاملIntegrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones
The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this area is still limited. Several lines of investigation have been used to elucidate the structure and function of the genes in the human genome. Even so, gene prediction remains a difficult task, as th...
متن کاملCorrection: Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones
Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones Tadashi Imanishi , Takeshi Itoh , Yutaka Suzuki, Claire O’Donovan , Satoshi Fukuchi, et al. DOI: 10.1371/journal.pbio.0020162 1. The abbreviation FLJ was expanded incorrectly (as full-length long Japan) in the abbreviations list and in the fi rst paragraph of the Results/Discussion section. FLJ stands for full-len...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genome Research
سال: 1999
ISSN: 1088-9051
DOI: 10.1101/gr.9.11.1135